DNA Primase Subunit 1 Expression in Hepatocellular Carcinoma and Its Clinical Implication

Table 4

Pathways were enriched in the PRIM1 expression differential phenotype.

Gene set name	NES	NOM val	FDR val
Cell cycle	2.289	<0.001	<0.001
Oocyte meiosis	2.182	<0.001	<0.001
p53 signaling pathway	1.987	<0.001	0.005
Wnt signaling pathway	1.837	0.004	0.018
MTOR signaling pathway	1.832	<0.001	0.017
ERBB signaling pathway	1.825	0.006	0.017
Phosphatidylinositol signaling system	1.769	0.004	0.020
Notch signaling pathway	1.761	0.008	0.021
RIG-I-like receptor signaling pathway	1.790	0.002	0.019
Complement and coagulation cascades	-2.164	<0.001	<0.001
Primary bile acid biosynthesis	-1.711	0.019	0.177
Fatty acid metabolism	-1.687	0.027	0.149

Notes: PRIM1: DNA Primase Subunit 1; ES: enrichment score; NES: normalized ES; NOM val: normalized value.