Clinicopathological Analysis of Five Cases of NUT Midline Carcinoma, including One with the Gingiva

Figure 2

NUT carcinoma histological features. NUT carcinomas of the gingiva exhibit fragmented tissue and tumor cell clusters, with locally visible bone fragments present within the gingiva (10x) (a). Poorly differentiated tumor cells with large nuclei are evident in dense clusters separated by fibrous stroma in another region of the gingival NMC tumor (40x) (b). Abrupt regions of focal keratinization are evident in the case of orbital NMC (100x) (c). Focal necrosis is evident in the case of laryngeal NMC (d). Neutrophil infiltration is prominent in the case or laryngeal NMC (200x) (e). Focal squamous differentiation is evident in the case of orbital NMC (100x) (f).

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