Clinicopathological Analysis of Five Cases of NUT Midline Carcinoma, including One with the Gingiva

Figure 3

NUT carcinoma immunohistochemical and molecular features. Diffuse nuclear NUT IHC staining for the case of gingival NUT carcinoma (100x) (a), laryngeal NUT carcinoma (100x) (b), orbital NUT carcinoma (100x) (c), and lung NUT carcinoma (100x) (d). Diffuse nuclear EGFR IHC staining for the case of lung NUT carcinoma (100x) (e). NUT break-apart probe FISH revealed the presence of distinct red and green signals consistent with NUT gene translocations in all 5 cases (1000x) (f).

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