Research Article

Toxoplasma gondii Tyrosine-Rich Oocyst Wall Protein: A Closer Look through an In Silico Prism

Table 4

Mouse specific MHC-II epitopes predicted by IEDB server with subsequent screening for antigenicity and allergenicity as well as IFN-γ and IL-4 induction.

Mouse MHC-II allelesT-cell peptideAntigenicityAllergenicityIFN-γ inductionIL-4 induction
ResultScoreResultScore

H2-IAb (MHC-II)PDNALAGAPQNEVAA1.2048YesNegative-0.6321Negative-1.02
TPDNALAGAPQNEVA0.9905NoNegative-0.6006Negative-1.01
RKKRVRGTGAPCSCA2.1439NoNegative-0.249Positive0.39
H2-IAd (MHC-II)IKILLLLGLLAVTTR0.6131NoNegative4Negative-0.75
LTSDSEKVAASSNLT1.2417YesNegative2Negative-0.38
SDSEKVAASSNLTPD1.0754NoNegative2Negative-0.41
H2-IEd (MHC-II)SFIECDCRKKRVRGT1.8125NoNegative-0.3691Positive0.29
CDCRKKRVRGTGAPC1.7682NoPositive1Positive0.29
ADLVKEAFRHSLLPW0.7519YesPositive1Positive0.23