miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1

Figure 1

miR-149 is downregulated in gastric cancer (GC) tissues and cell lines. (a) Expression analysis of miR-149 expression in GC tissues () and normal tissues () was performed in TCGA database. (b) qRT-PCR showed that miR-149 expression significantly decreased in GC tissues compared with that in normal gastric tissues (). (c) qRT-PCR was performed to analyze the miR-149 expression in GC cell lines (AGS MKN28, BGC-823, MKN45, and SGC-7901)) and a normal gastric epithelial cell line (GES-1). Differences between groups were evaluated using Student’s -test, and data are expressed as . For all data, indicates , and indicates .

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