Preparation of ¹⁷⁷Lu-PSMA-617 in Hospital Radiopharmacy: Convenient Formulation of a Clinical Dose Using a Single-Vial Freeze-Dried PSMA-617 Kit Developed In-House

Table 1

Variation of radiochemical purity of ¹⁷⁷Lu-PSMA-617 with the addition of increasing amount of carrier Lu in the PSMA-617 kit vial.

Amount of radioactive Lu in μg	Amount of nonradioactive Lu in μg	Ligand to metal ratio ()	Percentage radiochemical purity
1 (20 mCi, 740 MBq)	3.2	4 : 1
1 (20 mCi, 740 MBq)	4.6	3 : 1
1 (20 mCi, 740 MBq)	5.7	2.5 : 1
1 (20 mCi, 740 MBq)	7.4	2 : 1

Amount of PSMA-617 in the kit vial is 100 μg (95.9 nmol).