Research Article
Importance of KIM-1 and MCP-1 in Determining the Leptospirosis-Associated AKI: A Sri Lankan Study
Table 2
Patient characteristics by AKI status.
| | Characteristics and hematological/biochemical parameter | All cases () | Leptospirosis-confirmed patients () | Leptospirosis-unconfirmed patients () | | AKI () | Non-AKI () | value | AKI () | Non-AKI () | value | AKI () | Non-AKI () | value |
| | Gender, male (%) | 88.00 | 91.03 | 0.6329 | 89.47 | 86.66 | 0.7498 | 83.33 | 94.11 | 0.3067 | | Median | | Age (years) | 50.00 (29.50) | 43.00 (21.50) | 0.0275 | 50.00 (28.00) | 48.50 (22.75) | 0.1799 | 53.50 (40.75) | 42.00 (23.50) | 0.3817 | | WBC ( mm3) | 14.20 (9.18) | 9.37 (6.09) | 0.0003 | 12.94 (7.07) | 9.61 (5.85) | 0.0030 | 16.47 (13.22) | 9.35 (6.44) | 0.0715 | | Neutrophils (%) | 88.75 (10.28) | 80.10 (19.69) | <0.0001 | 89.35 (7.08) | 83.54 (20.38) | 0.0024 | 85.32 (9.63) | 78.92 (20.92) | 0.1087 | | Lymphocytes (%) | 7.02 (7.52) | 11.90 (15.05) | <0.0001 | 4.88 (6.89) | 11.45 (15.74) | 0.0004 | 8.39 (5.16) | 12.89 (13.85) | 0.1874 | | Creatinine (60-120 μmol/l) | 367.7 (313.10) | 98.00 (41.15) | <0.0001 | 443.40 (315.10) | 101.60 (52.20) | <0.0001 | 233.30 (168.42) | 94.85 (38.30) | <0.0001 | | BUN (2.5-6.5 mmol/l) | 22.80 (17.73) | 7.30 (4.95) | <0.0001 | 26.96 (25.26) | 7.75 (6.72) | <0.0001 | 12.10 (11.97) | 7.22 (4.45) | 0.0495 | | SGOT (10-40 U/l) | 69.00 (52.55) | 47.60 (53.80) | 0.0267 | 80.50 (53.80) | 59.30 (58.17) | 0.2384 | 52.40 (111.10) | 42.00 (36.75) | 0.3989 | | SGPT (13-31 U/l) | 101.3 (119.47) | 50.75 (46.57) | 0.0092 | 106.90 (100.60) | 62.50 (50.65) | 0.0438 | 67.70 (124.00) | 47.50 (31.6) | 0.3107 | | Na+ (136-145 mmol/l) | 133.20 (9.70) | 136.0 (6.00) | 0.4072 | 132.60 (10.9) | 135.80 (8.2) | 0.5106 | 136.50 (6.15) | 136.40 (4.90) | 0.8838 | | Total bilirubin (5-21 μmol/l) | 35.72 (124.94) | 15.32 (25.40) | 0.0087 | 59.24 (176.69) | 13.33 (23.78) | 0.0063 | 17.30 (19.49) | 18.46 (29.77) | 0.9969 | | Direct bilirubin (3.4 μmol/l) | 21.54 (85.83) | 7.440 (11.03) | 0.0050 | 34.65 (142.93) | 6.33 (9.69) | 0.0112 | 10.69 (7.92) | 7.80 (11.22) | 0.4573 | | CRP (<0.5 mg/l) | 189.90 (99.90) | 131.40 (141.20) | 0.0003 | 189.90 (77.35) | 157.30 (155.32) | 0.0197 | 181.30 (153.95) | 114.90 (135.20) | 0.0737 | | Mean | | Hemoglobin (14.0-17.5 g/dl) | | | 0.0098 | | | 0.1402 | | | 0.1107 | | Platelet () | | | 0.0083 | | | 0.0277 | | | 0.4666 | | K+ (3.5-5.2 mmol/l) | | | 0.0012 | | | 0.0040 | | | 0.0766 |
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: Mann-Whitney test and unpaired -test. |
