Identification of Potential Genetic Biomarkers and Target Genes of Peri-Implantitis Using Bioinformatics Tools

Table 2

Top 10 hub genes with higher degree of connectivity.

Gene symbol	Gene description	Degree
IL-6	Interleukin-6	46
TLR4	Toll-like receptor 4	43
FN1	Fibronectin 1	33
IL-1β	Interleukin-1 beta	32
CXCL8	C-X-C motif chemokine ligand 8	32
MMP-9	Matrix metallopeptidase-9	31
CXCR4	C-X-C motif chemokine receptor 4	30
CXCL1	C-X-C motif chemokine ligand 1	27
PECAM1	Platelet and endothelial cell adhesion molecule 1	26
SPP1	Secreted phosphoprotein 1	22