Research Article

Prognostic Significance of CD56 Antigen Expression in Patients with De Novo Non-M3 Acute Myeloid Leukemia

Table 1

Clinical characteristics of de novo non-M3 AML patients according to the CD56 expression.

VariablesAll patients, (%)CD56-low, (%)CD56-high, (%) value

No. of patients89 (100)63 (70.79)26 (29.21)
Sex
 Male42 (47.19)24 (38.10)18 (69.23)0.343
 Female47 (52.81)39 (61.90)8 (30.77)
Age, years0.143
 Mean (min-max)39 (12~64)41 (13~64)36 (12~61)
BM blasts (%)0.244
 Median67.7063.3973.20
 Range15.57~97.2515.57~97.2533.50~95.00
WBC (×109/L)0.632
 Mean (min-max)39.76 (0.59~365.67)41.55 (0.95~365.67)35.19 (1.28~148.90)
HB (g/dL)0.336
 Mean (min-max)76.03 (1.78~149.00)77.71 (1.78~149.00)71.65 (37~107)
PLT (×109/L)0.010
 Median27.0032.521.5
 Range3~3013~3015~83
FAB classification0.471
 M19 (10.11)5 (7.94)4 (15.38)
 M227 (30.34)20 (31.75)7 (26.92)
 M428 (31.46)24 (38.10)4 (15.38)
 M515 (16.85)11 (17.46)4 (15.38)
 Unclassified5 (5.62)3 (4.76)2 (7.69)
Cytogenetic risk0.274
 Favorable9 (10.11)5 (7.94)4 (15.38)
 Intermediate61 (68.54)43 (68.25)18 (69.23)
 Adverse19 (21.35)15 (23.81)4 (15.38)
Received BMT1.000
 BMT15 (16.85)11 (17.46)4 (15.38)
 Without BMT74 (83.15)52 (82.54)22 (84.62)

BM: bone marrow; WBC: white blood cell; Hb: hemoglobin; PLT: platelet; BMT: bone marrow transplantation.