Research Article

Correlation of Neuroimaging Findings with Clinical Presentation and Laboratory Data in Patients with COVID-19: A Single-Center Study

Table 1

Comparison of characteristics of patients with and without abnormal brain imaging result.

VariablesOverall ()Abnormal brain imaging result group ()aNormal brain imaging result group ()b valueAbnormal brain imaging result group ()cNormal brain imaging result group ()d value

Age (years)67 (54-76)69.5 (53-79)66.0 (54-75)0.44871.0 (60-79)63.0 (44-73)<0.001
Gender, male245 (56.2)32 (69.6)213 (54.6)0.053129 (68.3)116 (47.0)<0.001
Hospitalization329 (75.5)42 (91.3)287 (73.6)0.008160 (84.7)169 (68.4)<0.001
Any comorbidity294 (67.4)37 (80.4)257 (65.9)0.047146 (77.2)148 (59.9)<0.001
Hypertension230 (52.8)29 (63.0)201 (51.5)0.139113 (59.8)117 (47.4)0.010
Previous cerebrovascular disease59 (13.5)9 (19.6)50 (12.8)0.20638 (20.1)21 (8.5)<0.001
Cardiovascular disease89 (20.4)11 (23.9)78 (20.0)0.53347 (24.9)42 (17.0)0.044
Renal insufficiency32 (7.3)8 (17.4)24 (6.2)0.01221 (11.1)11 (4.5)0.008
Diabetes mellitus93 (21.3)12 (26.1)81 (20.8)0.40544 (23.3)49 (19.8)0.385
COPD38 (8.7)1 (2.2)37 (9.5)0.16015 (7.9)23 (9.3)0.614
Any immunosuppression10 (2.2)5 (10.8)5 (1.3)<0.0017 (3.7)3 (1.2)0.656
Indications for brain imaging0.239<0.001
Altered mental status247 (56.7)28 (60.9)219 (56.2)123 (65.1)124 (50.2)
Syncope52 (11.9)3 (6.5)49 (12.6)10 (5.3)42 (17.0)
Neurological deficit74 (17.0)13 (28.3)61 (15.6)39 (20.6)35 (14.2)
Seizure9 (2.1)0 (0)9 (2.3)2 (1.1)7 (2.8)
Head trauma12 (2.8)0 (0)12 (3.1)3 (1.6)9 (3.6)

Statistically significant. Values are presented as median (interquartile range) for continuous variables and frequency (percentage) for categorical variables. COPD: chronic obstructive pulmonary disease. aGroup 1, bGroup 2, cGroup 3, and dGroup 4.