Correlation of Neuroimaging Findings with Clinical Presentation and Laboratory Data in Patients with COVID-19: A Single-Center Study
Table 1
Comparison of characteristics of patients with and without abnormal brain imaging result.
Variables
Overall ()
Abnormal brain imaging result group ()a
Normal brain imaging result group ()b
value
Abnormal brain imaging result group ()c
Normal brain imaging result group ()d
value
Age (years)
67 (54-76)
69.5 (53-79)
66.0 (54-75)
0.448
71.0 (60-79)
63.0 (44-73)
<0.001
Gender, male
245 (56.2)
32 (69.6)
213 (54.6)
0.053
129 (68.3)
116 (47.0)
<0.001
Hospitalization
329 (75.5)
42 (91.3)
287 (73.6)
0.008
160 (84.7)
169 (68.4)
<0.001
Any comorbidity
294 (67.4)
37 (80.4)
257 (65.9)
0.047
146 (77.2)
148 (59.9)
<0.001
Hypertension
230 (52.8)
29 (63.0)
201 (51.5)
0.139
113 (59.8)
117 (47.4)
0.010
Previous cerebrovascular disease
59 (13.5)
9 (19.6)
50 (12.8)
0.206
38 (20.1)
21 (8.5)
<0.001
Cardiovascular disease
89 (20.4)
11 (23.9)
78 (20.0)
0.533
47 (24.9)
42 (17.0)
0.044
Renal insufficiency
32 (7.3)
8 (17.4)
24 (6.2)
0.012
21 (11.1)
11 (4.5)
0.008
Diabetes mellitus
93 (21.3)
12 (26.1)
81 (20.8)
0.405
44 (23.3)
49 (19.8)
0.385
COPD
38 (8.7)
1 (2.2)
37 (9.5)
0.160
15 (7.9)
23 (9.3)
0.614
Any immunosuppression
10 (2.2)
5 (10.8)
5 (1.3)
<0.001
7 (3.7)
3 (1.2)
0.656
Indications for brain imaging
—
—
—
0.239
—
—
<0.001
Altered mental status
247 (56.7)
28 (60.9)
219 (56.2)
123 (65.1)
124 (50.2)
Syncope
52 (11.9)
3 (6.5)
49 (12.6)
10 (5.3)
42 (17.0)
Neurological deficit
74 (17.0)
13 (28.3)
61 (15.6)
39 (20.6)
35 (14.2)
Seizure
9 (2.1)
0 (0)
9 (2.3)
2 (1.1)
7 (2.8)
Head trauma
12 (2.8)
0 (0)
12 (3.1)
3 (1.6)
9 (3.6)
Statistically significant. Values are presented as median (interquartile range) for continuous variables and frequency (percentage) for categorical variables. COPD: chronic obstructive pulmonary disease. aGroup 1, bGroup 2, cGroup 3, and dGroup 4.