Crosstalk between Heart Failure and Cognitive Impairment via hsa-miR-933/RELB/CCL21 Pathway

Figure 5

Heatmap of DE-miRNAs’ factor in predicting cognitive impairment and the expression of their targeted DE-mRNAs in the models. (a) Heatmap of DE-miRNA expression shows the expression of 5 DE-miRNAs predictive of cognitive impairment in the prediction model. (b) Heatmap of DE-mRNA expression shows the expression of DE-mRNA targeted by the five predictors in the model of patients with cognitive impairment, Alzheimer’s disease (AD), vascular dementia (VaD), Dementia with Lewy Bodies (DLB), Mild Cognitive Impairment (MCI), and dementia (D).

(a)

(b)