Role of SNPs in the Biogenesis of Mature miRNAs

Figure 9

Distribution of SNP-pre-miRNAs between nor-SNP-pre-miRNA and iso-SNP-pre-miRNA based on SNP-caused free energy change of pre-miRNA.

(a) Free energy change of the P5_5-associated pre-miRNA (kcal/mol)

(b) Free energy change of the P5_3-associated pre-miRNA (kcal/mol)

(c) Free energy change of the P3_5-associated pre-miRNA (kcal/mol)

(d) Free energy change of the P3_3-associated pre-miRNA (kcal/mol)