Zishen Qingre Tongluo Formula Improves Renal Fatty Acid Oxidation and Alleviated Fibrosis via the Regulation of the TGF-<i>β</i>1/Smad3 Signaling Pathway in Hyperuricemic Nephrology Rats

<div>Effects of ZQTF on fibrosis and fatty acid oxidation in renal tissues. (a) Effect of ZQTF on protein levels of fibronectin, collagen 1, PGC-1<i>α</i>, PPAR<i>γ</i>, PPAR<i>α</i>, P-Smad3, and Smad3 by western blot analysis. (b) Effect of ZQTF on mRNA levels of TGF-<i>β</i>1, fibronectin, collagen 1, PGC-1<i>α</i>, PPAR<i>γ</i>, and PPAR<i>α</i> by real-time PCR analysis. 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BioMed Research International

fig4

Figure 4

Figure 4: Zishen Qingre Tongluo Formula Improves Renal Fatty Acid Oxidation and Alleviated Fibrosis via the Regulation of the TGF-<i>β</i>1/Smad3 Signaling Pathway in Hyperuricemic Nephrology Rats 

Figure 4 | Zishen Qingre Tongluo Formula Improves Renal Fatty Acid Oxidation and Alleviated Fibrosis via the Regulation of the TGF-β1/Smad3 Signaling Pathway in Hyperuricemic Nephrology Rats 