Research Article
Development of a Population Pharmacokinetic Model for Cyclosporine from Therapeutic Drug Monitoring Data
| | Group A | Group B |
| Total number of patients | 37 | 16 | Number of observations | 621 | 81 | Sex (male/female) | 16/21 | 6/10 | Age (, years) | | | BW (, kg) | | | Serum Cr (mean, mg/dL) | 1.11 (5.9-0.2) | 1.71 (7.71-0.36) | Cl Cr (mean, mL/min) | 98.62 (417.92-13.79) | 98.56 (240.05-7.71) | Reason of treatment | Kidney transplant (14) Liver autoimmune diseases (1) Bone marrow transplant (1) Kidney autoimmune diseases (21) | Kidney autoimmune diseases (8) Bone marrow transplant (2) Kidney transplant (5) Erythroblastopenia (1) |
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