Research Article
Establishment and Validation of the Detection of TERT Promoter Mutations by Human Gliomas U251 Cell Lines
Figure 4
The frequency of TERTp mutations in glioma samples. (a) The frequency of TERTp C228T and C250T mutations in each glioma type (DA, AA, AO, OA, O, and GBMs). (b) The frequency of TERTp mutations in FFPE and frozen tissues. TERTp: the promoter region of the telomerase reverse transcriptase gene. DA: diffuse astrocytoma; AA: anaplastic astrocytoma; AO: anaplastic oligodendroglioma; OA: oligoastrocytoma; O: oligodendroglioma; GBMs: glioblastomas; FFEP: formalin fixed paraffin-embedded; TERTp-mut: TERT promoter mutation; TERTp-wt: TERT promoter wild type.
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