Research Article
[Retracted] Effect of Tumor Microenvironment and Angiogenesis on Clinical Outcomes of Primary Central Nervous System Lymphoma
Table 1
Biological process, molecular functions, and KEGG pathways of candidate genes.
| Category | Genes in pathway | value | FDR | % in pathway | Genes |
| Biological process | GO:0002042~cell migration during sprouting angiogenesis | 4 | 0.003 | 0.008 | 25.0 | ROBO1 | GO:0016568~chromatin modification | 104 | 0.004 | 0.008 | 1.9 | KAT2B; SETD1B | GO:0001569~patterning of blood vessels | 8 | 0.007 | 0.008 | 12.5 | GNA13 | GO:0035264~multicellular organism growth | 8 | 0.007 | 0.008 | 12.5 | APBA1 | GO:0043542~endothelial cell migration | 8 | 0.007 | 0.008 | 12.5 | ROBO1 | Molecular function | GO:0031701~angiotensin receptor binding | 5 | 0.004 | 0.007 | 20.0 | GNA13 | GO:0031702~type 1 angiotensin receptor binding | 5 | 0.004 | 0.007 | 20.0 | GNA13 | GO:0005546~phosphatidylinositol-4,5-bisphosphate binding | 7 | 0.006 | 0.007 | 14.3 | APBA1 | Biological pathways1 | IL-1 signaling | 91 | 0.003 | 0.007 | 2.2 | GNA13; MYD88 |
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1Biological pathways were annotated according to the Kyoto Encyclopedia of Genes and Genomes (KEGG) library. FDR: false discovery rate.
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