Differences of Key Proteins between Apoptosis and Necroptosis

Figure 3

CASP8, RIPK1, and RIPK3 effect on apoptosis and necroptosis. Caspase-8 plays a role in apoptosis and necroptosis. In apoptosis, caspase-3 is cleaved to cause apoptosis, and in necroptosis, RIPK1 is inhibited to prevent necroptosis.