Exploring the Operative Strategy for Secondary Mitral Regurgitation: A Systematic Review

Table 5

Studies comparing subvalvular repair plus RMA vs. RMA alone.

First author (ref. #)	Number of patients	Follow-up (yrs)	Type of surgery	Main findings
Furukawa et al. [8]	36	5	RMA plus SVR/RMA; 22/14	Few rate of MR recurrence in SVR. Improvement in LV remodeling
Harmel et al. [10]	50	1	RMA plus SVR/RMA; 50/50	Higher survival rate in SVR
Nappi et al. [9]	96	5	RMA plus SVR/RMA; 48/48	Better improvement LV remodeling and MV geometry in SVR
Wakasa et al. [68]	90	6,4	RMA plus SVR/RMA; 60/30	Better improvement LV remodeling and function in SVR and LV reconstruction
Roshanali et al. [71]	90	5	RMA plus SVR/RMA; 60/30	Few rate of MR recurrence and better improvement in survival in SVR
Fattouch et al. [70]	110	5	RMA plus SVR/RMA; 55/55	Few rate of MR recurrence in SVR
Hvass et al. [7]	37	7	SVR/RMA; 37	Few rate of MR recurrence in SVR and significant improvement in leaflet tethering
Shudo et al. [40]	16	3,5	RMA plus SVR/RMA; 15/11	Significant improvement in leaflet tethering in SVR
Langer et al. [61]	60	2	RMA plus SVR/RMA; 30/30	Few rate of MR recurrence and reoperation in SVR. Significant improvement in leaflet tethering

RMA: restrictive mitral annuloplasty; SVR: subvalvular repair. See text for other abbreviation.