Short-Term Effects of Supplemental L-Arginine, Diosmin, Troxerutin, and Hesperidin in Diabetic Patients: A Pilot Study

Table 1

Composition of the dietary supplement Flebotrofine®.

Component	Dose (mg)
L-Arginine	500
Troxerutin 95% of which troxerutin	315.8; 300
Diosmin 80%—Microsmin plus of which diosmin	375; 300
Black currant (extract)	200
Hesperidin 98% of which hesperidin	102.04; 100
Centella asiatica 2% (extract)	50
Citric acid	750
Maltodextrin	1,513.16
Sucralose	11
Flavor	300
Fruitmax cranberry 712	140
Silicon dioxide	43
Total	4,300

ADMA: N^G,N^G,Dimethyl-L-arginine; DDAH: dimethylarginine dimethylaminohydrolase; eNOS: endothelial nitric oxide synthase; L-Arg: L-arginine; NO: nitric oxide; PRMT: protein arginine methyltransferase; SDMA: symmetric dimethylarginine.