First Evidence from Sri Lanka for Subphenotypic Diversity within L. donovani-Induced Classical Cutaneous Leishmaniasis
Table 2
Comparison of progressive (early ulcerating lesions: UTs) and silent lesions (late nonulcerating lesions: NUTs).
Clinical characteristics
Progressive lesions UTs of ≤3 months
Silent lesions NUTs of >9 months
value#
Count
(%)
Count
(%)
Geographical origin
Northern region
17
(15.2)
21
(47.7)
≤0.001
Southern region
95
(84.8)
23
(52.3)
Total
112
(100.0)
44
(100.0)
Age (years)
Up to 20
22
(19.6)
15
(34.1)
0.002
21-40
44
(39.3)
24
(54.5)
Over 40
46
(41.1)
5
(11.4)
Total
112
(100.0)
44
(100.0)
Number of lesions
Single
104
(92.9)
34
(77.3)
0.006
Multiple
8
(7.1)
10
(22.7)
Total
112
(100.0)
44
(100.0)
Size of lesion
≤2 cm
62
(55.4)
34
(77.3)
0.011
>2 cm
50
(44.6)
10
(22.7)
Total
112
(100.0)
44
(100.0)
Shape of lesion
Rounded
53
(47.3)
33
(75.0)
0.002
Shape altered
59
(52.7)
11
(25.0)
Total
112
(100.0)
44
(100.0)
Color of lesion
No change
1
(0.9)
7
(15.9)
0.002
Erythematous
74
(67.0)
25
(56.8)
Hyperpigmented
27
(24.1)
8
(18.2)
Hypopigmented
10
(8.9)
4
(9.1)
Total
112
(100.0)
44
(100.0)
Other associations
—
Squamation of skin
Observed
14
(48.3)
5
(20.0)
Sporotrichoid lesions
Observed
1
(3.6)
3
(12.0)
Satellite lesions
Observed
4
(14.3)
2
(8.0)
Skin hyperpigmentation
Observed
4
(14.3)
1
(4.0)
Skin hypopigmentation
Observed
8
(28.6)
8
(32.0)
Skin inflammation
Observed
5
(17.9)
2
(8.0)
From the early lesion group, data pertaining only to relevant categories within each variable are shown ( values were not calculated). # values were calculated using online statistical program, VassarStats (available on http://vassarstats.net/).
