Melatonin Alleviated Potassium Dichromate-Induced Oxidative Stress and Reprotoxicity in Male Rats

Figure 4

Photomicrograph of the testis section of rat stained with p53 immunohistochemical stain. Brown-stained nuclei indicates positive stain for p53. (a) The control group showing negative staining. (b) The potassium dichromate group showing increase of p53 expression in spermatogenic cells. (c) The potassium dichromate and melatonin low-dose group showing a moderate decrease of p53 reaction. (d) The potassium dichromate and melatonin high-dose group showing a marked decrease of p53 reaction. (e) The melatonin group showing negative staining (p53 immune staining: ×400).

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