Cytotoxic and Antifungal Amides Derived from Ferulic Acid: Molecular Docking and Mechanism of Action

Table 3

Results of the mechanisms of action: effects of compounds 10 and 11 in the presence or absence of a protective osmotic (sorbitol 0.8 M), as well as in the presence or absence of ergosterol.

Compounds	With ergosterol	Without ergosterol	With sorbitol	Without sorbitol
10	62.25 μg/mL	62.25 μg/mL	>1000 μg/mL	31.25 μg/mL
11	62.25 μg/mL	62.25 μg/mL	>1000 μg/mL	15.62 μg/mL
Caspofungin	—	—	1 μg/mL	0.015 μg/mL
Nystatin	31.25 μg/mL	3.75 μg/mL	—	—