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BioMed Research International
/
2021
/
Article
/
Tab 1
/
Research Article
Novel Elongator Protein 2 Inhibitors Mitigating Tumor Necrosis Factor-
α
Induced Osteogenic Differentiation Inhibition
Table 1
Affinity constants of candidate compounds with ELP2 protein.
No.
Protein
Compound
Avg
(M
-1
s
-1
)
Avg
(s
-1
)
Avg KD (M)
1#
Elp2
1#
2#
Elp2
2#
3#
Elp2
3#
4#
Elp2
4#
5#
Elp2
5#
6#
Elp2
6#
7#
Elp2
7#
8#
Elp2
8#
9#
Elp2
9#
10#
Elp2
10#
11#
Elp2
11#
Blank
Elp2
DMSO