Development of a 15-Gene Signature Model as a Prognostic Tool in Sex Hormone-Dependent Cancers

Figure 1

The workflow of this study. First, the gene module related to the luminal A-like phenotype was identified, and its applicability to other sex hormone-dependent cancer types was assessed. Next, module hub genes screened using LASSO were used to construct a gene signature model for the assessment of the luminal A-like phenotype. Finally, the model’s relationship with prognosis, enriched pathways, and immune infiltration was investigated using bioinformatics approaches.