Research Article

Formulation, Optimization, In Vitro and In Vivo Evaluation of Saxagliptin-Loaded Lipospheres for an Improved Pharmacokinetic Behavior

Table 6

The results of studied pharmacokinetic parameters of SG-loaded optimized lipospheres and SG reference brand.

Pharmacokinetic variablesGroup A SG-OLGroup B SG-brand

(h)
(ng/mL)
MRT0-24 (h)
AUC0-24 (ng.h/mL)
(h)
(h-1)
AUC0-∞ (ng.h/mL)
AUMC0-∞ (ng.h/mL)