Design and Optimization of Cationic Nanocapsules for Topical Delivery of Tretinoin: Application of the Box-Behnken Design, In Vitro Evaluation, and Ex Vivo Skin Deposition Study

Table 7

Size, PDI, zeta potential, and EE% of encapsulated TTN as a function of storage time. Results are shown as ().

Temperature	Day of storage	Size (nm)	PDI	Zeta potential (mV)	EE (%)
4°C temperature	0
	30
	60
	90
Room temperature	0
	30
	60
	90