PLOD3 Is Associated with Immune Cell Infiltration and Genomic Instability in Colon Adenocarcinoma

Figure 1

PLOD3 is upregulated in COAD. The RNA and protein expression of PLOD3 are upregulated in the COAD samples of (a) TCGA and (b) CPTAC cohorts, respectively. (, , , and ). (c) The PLOD3 promoter is hypomethylated in COAD samples of TCGA cohort. (d) The promoter DNA methylation and RNA expression of PLOD3 are negatively correlated in TCGA cohort. The line was fitted by using RNA expression and DNA methylation of PLOD3 as response and predictor variables, respectively. The symbol indicates the value <0.001 (log2 FC: log2 fold change).

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