Analysis of Pepsin Concentration and Influencing Factors in Saliva of Elderly Nasal Feeding Patients
Table 1
Demographic and clinical characteristics of the 133 enrolled patients.
Variables
Pepsin μg/mla ()
Pepsin μg/ml ()
Age (year)
0.220
Esophageal hiatal hernia
2 (3.63)
2 (2.56)
0.721
Hyperlipidemia
7 (12.72)
11 (14.10)
0.819
Family history of gastroesophageal disease
4 (7.27)
7 (8.97)
0.726
OSAS
1 (1.82)
1 (1.28)
0.802
Drugs related to GERDb
16 (29.09)
29 (37.18)
0.332
Diabetes
14 (25.45)
35 (44.87)
0.022
Hypertension
38 (69.09)
48 (61.54)
0.370
Mechanical ventilation
19 (34.55)
36 (46.15)
0.213
Total daily feeding volume (ml)
0.297
≤500
6 (10.91)
16 (20.51)
501-1500
35 (63.63)
47 (60.26)
>1500
14 (25.45)
15 (19.23)
Feeding method
0.028
Syringe injection
36 (65.45)
36 (46.15)
Nasal pump feeding
19 (34.55)
42 (53.85)
Insertion length/height
0.774
<0.35
24 (43.64)
36 (46.15)
≥0.35
31 (56.36)
42 (53.85)
Tube diameter (mm)
0.092
4.46
30 (4.55)
31 (39.74)
3.23
25 (45.45)
47 (60.26)
Stomach tube placement time (day)
0.062
≥512c
22 (0.4)
44 (56.41)
<512
33 (0.6)
34 (43.59)
OSAS: obstructive sleep apnea syndrome; GERD: gastroesophageal reflux disease. a7.75 μg/ml is the median of pepsin content. bMainly including nonsteroidal anti-inflammatory drugs, aspirin, and anticholinergic agents. c512 days is the median time of stomach tube placement (day).
