Bone Marrow-Derived Mesenchymal Stem Cells Differentially Affect Glioblastoma Cell Proliferation, Migration, and Invasion: A 2D-DIGE Proteomic Analysis

Table 1

Upregulated protein expression and downregulated protein expression in C6-A_3-3 compared with C6 cells.

Spot	Accession no.	Entry name	Protein name	%Cov	PI	MW (kDa)	FC	Protein score	test, value
Increased protein expression
1	P31000	Vim	Vimentin	36	5.06	53.76	1.62	79	0.0017
2	Q6AYZ1	Tuba1c	Tubulin alpha-1C chain	27	4.96	50.59	1.52	63	0.0035
3	Q63081	Pdia6	Protein disulfide isomerase A6	41	4.95	48.49	1.71	175	0.0218
4	Q91V26	Sphk1	Sphingosine kinase 1	25	6.64	42.89	1.79	132	0.0183
5	P55260	Anxa4	Annexin A4	38	5.31	36.17	1.58	85	0.0415
Decreased protein expression
6	P18418	Calr	Calreticulin	21	4.33	48.14	-1.51	103	0.0021
7	P04182	Oat	Ornithine aminotransferase	48	6.57	48.85	-1.75	147	0.0478
8	I6L9G6	Tardbp	TAR DNA-binding protein 43	29	5.85	45.05	-1.75	98	0.0196
9	B2RYJ7	Actr1b	Beta-centractin	25	5.98	42.38	-1.71	81	0.0361
10	Q63945	Set	SET	33	4.23	33.47	-1.87	161	0.0347
11	O08557	Ddah1	Dimethylarginine dimethylaminohydrolase 1	45	5.53	31.44	-1.67	127	0.0078
12	Q9QXQ0	Actn4	Alph-actinin-4	24	5.27	105.24	-1.62	168	0.0029
13	P13084	Npm1	Nucleophosmin	31	4.46	32.73	-1.96	119	0.0291
14	Q920J4	Txnl1	Thioredoxin-like protein 1	46	4.84	32.63	-1.52	91	0.0085
15	P58775	Tpm2	Tropomyosin beta chain	37	4.66	32.94	-1.62	182	0.0140
16	D4A7Q5	Ddx28	Probable ATP-dependent RNA helicase DDX28	43	10.43	59.74	-1.51	73	0.0382
17	D3ZK56	Rap2c	Ras-related protein Rap-2c	37	4.87	20.96	-2.34	153	0.0409

FC: fold change = C6-A_3-3/C6.