Research Article

Distribution and Afferent Effects of Transplanted mESCs on Cochlea in Acute and Chronic Neural Hearing Loss Models

Table 1

Status of organ of Corti and Rosenthal’s canal in each animal after experiment.

GroupAnimal no.Organ of CortiRosenthal’s canal

KM only#3KSupporting cell remainsTotal SGN loss
#4KSupporting cell remainsTotal SGN loss
#5KFlat epitheliumTotal SGN loss
#16KSupporting cell remainsIntact SGN density
#17KSupporting cell remainsIntact SGN density
Ouabain only#2OSupporting cell remainsIntact SGN density
#3OSupporting cell remainsPartial SGN loss
#12OSupporting cell remainsPartial SGN loss
#2KSSupporting cell remainsPartial SGN loss
#3 KSSupporting cell remainsPartial SGN loss
#9KSSupporting cell remainsIntact SGN density
#11KSSupporting cell remainsIntact SGN density
#17OSSupporting cell remainsIntact SGN density
#20OSSupporting cell remainsPartial SGN loss

KM: kanamycin; SC: stem cell; HC: hair cell; SGN: spiral ganglion neuron.