|
Symbol | Gene name | Network | Expression | CF-related | Tissue |
|
APP | Amyloid beta precursor protein | Bronchial | Down | — | — |
C3AR1 | Complement C3a receptor 1 | Bronchial | Up | Yes | Lung [62] |
CCL4 | C–C motif chemokine ligand 4 | Bronchial | Up | Yes | Lung [63], Tear fluid [64] |
CD53 | CD53 molecule | Bronchial | Up | Yes | Nasal (airway inflammation) [65], Lung [66] |
CDC16 | Cell division cycle 16 | Bronchial | Down | Yes | Blood neutrophils [67] |
CLU | Clusterin | Bronchial | Down | Yes | Lung (airway secretions) [68] |
CXCR4 | C–X–C motif chemokine receptor 4 | Bronchial | Up | Yes | Lung [69] |
FCER1G | Fc fragment of IgE receptor Ig | Bronchial | Up | Yes | Lung [66, 70], Pancreas [71], Intestine [72] |
FGR | FGR protooncogene, Src family tyrosine kinase | Bronchial | Up | Yes | Kidney [73] |
FPR1 | Formyl peptide receptor 1 | Bronchial | Up | — | — |
IL1B | Interleukin 1 beta | Bronchial | Up | Yes | Airway mucopurulent secretions [74, 75] |
NFKBIA | NFKB inhibitor alpha | Bronchial | Up | Yes | Bronchial gland cells [76], Lung [77] |
PLA2G4B | Phospholipase A2 group IVB | Bronchial | Down | Yes | Lung [78] |
PLAU | Plasminogen activator, urokinase | Bronchial | Up | Yes | Airway epithelia [79] |
PLAUR | Plasminogen activator, urokinase receptor | Bronchial | Up | Yes | Airway epithelia [79] |
PTAFR | Platelet activating factor receptor | Bronchial | Up | — | — |
S100A12 | S100 calcium-binding protein A12 | Bronchial | Up | Yes | Lung sputum [80–82] |
SAA1 | Serum amyloid A1 | Bronchial | Up | Yes | Lung fibroblasts [83], Lung [62, 78], Blood [84] |
TNFRSF1B | TNF receptor superfamily member 1B | Bronchial | Up | — | — |
UBC | Ubiquitin C | Bronchial | Down | — | — |
ACTB | Actin beta | Rectal | Up | Yes | Lung [13, 85] |
TUBB4B | Tubulin beta 4B class IVb | Rectal | Up | Yes | Airway epithelia [86], ciliated cells [86] |
YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | Rectal | Up | — | — |
|