Research Article
Study on the Mechanism of Acori Graminei Rhizoma in the Treatment of Alzheimer’s Disease Based on Network Pharmacology and Molecular Docking
Table 2
Topological values of core targets in protein-protein interaction networks.
| Core target | Betweenness centrality | Closeness centrality | Degree |
| APP | 0.36432506 | 0.72916667 | 23 | CASP3 | 0.12727436 | 0.66037736 | 18 | MAPK1 | 0.10814869 | 0.625 | 16 | MAPT | 0.05142191 | 0.60344828 | 14 | VEGFA | 0.05260249 | 0.58333333 | 12 | ACHE | 0.03699421 | 0.56451613 | 12 | GSK3B | 0.02680704 | 0.57377049 | 11 | ESR1 | 0.04004646 | 0.58333333 | 11 | LRRK2 | 0.01789274 | 0.56451613 | 11 | DRD2 | 0.03274326 | 0.53030303 | 10 |
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