[Retracted] Mangifera indica Extracts as Novel PKM2 Inhibitors for Treatment of Triple Negative Breast Cancer

Table 1

Preliminary screening of crude plant extract library for the identification of PKM2 inhibitors.

Sr. no.	Plant name	Family	Common name	Part used	Extract no.	PKM2 activity
1	Cyamopsis tetragonoloba (L.) Taub	Fabaceae	Guar gum	Seeds	1	−
2	Calotropis procera (Aiton) Dryand.	Apocynaceae	Sodom apple	Leaves	2	−
3	Azadirachta indica A. Juss.	Meliaceae	Indian lilac	Leaves	3	−
4	Ageratum conyzoides L.	Asteraceae	Goat weed	Whole plant	4	−
5	Dalbergia sissoo sensu Miq.	Fabaceae	Indian rosewood	Seeds	5	−
				Bark	6	−
6	Albizia lebbeck (L.) Benth.	Fabaceae	Lebbeck	Flowers	7	−
				Seeds	8	−
				Seed coat	9	−
				Leaves	10	+
7	Momordica charantia L.	Cucurbitaceae	Bitter melon	Vegetable	11	−
				Seeds	12	−
8	Oxalis corniculata L.	Oxalidaceae	Creeping woodsorrel	Whole plant	13	−
9	Cassia fistula L.	Fabaceae	Golden shower	Leaves	14	+
				Fruit	15	+
10	Aloe barbadensis Mill.	Asphodelaceae	Aloe vera	Whole plant	16	−
11	Nerium oleander L.	Apocynaceae	Oleander	Leaves	17	−
12	Chenopodium album L.	Amaranthaceae	Lamb’s quarters	Whole plant	18	−
13	Bombax ceiba L.	Malvaceae	Cotton tree	Leaves	19	−
				Bark	20	++
14	Cicer arietinum L.	Fabaceae	Chickpea (white)	Seed	21	−
			Chick pea (black)	Seed	22	−
15	Smilax china L.	Smilacaceae	China root	Roots	23	−
16	Eucalyptus camaldulensis Dehnh.	Myrtaceae	Himalayan poplar	Bark	24	−
17	Helianthus annuus L.	Asteraceae	Sun flower	Seeds	25	−
18	Artemisia absinthium L.	Asteraceae	Common wormwood	Whole plant	26	+
19	Litchi chinensis Sonn.	Sapindaceae	Lychee	Seeds	27	−
				Bark	28	+
				Leaves	29	−
20	Lawsonia inermis	Lythraceae	Henna	Leaves	30	−
21	Cyperus esculentus L.	Cyperaceae	Water grass	Flowers	31	−
22	Fagonia arabica L.	Zygophyllaceae	Dhamasa	Whole plant	32	−
23	Cucumis melo agrestis Naudin	Cucurbitaceae	Wild melon	Leaves	33	−
				Stem	34	−
24	Asphodelus tenuifolius Cav.	Asphodelaceae	Wild onion	Whole plant	35	−
25	Solanum nigrum L.	Solanaceae	Black nightshade	Whole plant	36	−
26	Mangifera indica L.	Anacardiaceae	Mango	Fruit pulp	37	−
				Peel	38	−
				Bark	39	++
				Seed coat	40	++
				Leaves	41	++
27	Trachyspermum ammi (L.) Sprague	Apiaceae	Carom seeds	Seeds	42	−
28	Ferula assa-foetida L.	Umbelliferae	Heng	Resin	43	−
29	Linum usitatissimum L.	Linaceae	Flax seeds	Seeds	44	−
30	Citrullus colocynthis (L.) Schrad.	Cucurbitaceae	Desert bitter gourd	Fruit	45	−
31	Trigonella foenum-graecum L.	Fabaceae	Fenugreek	Seeds	46	−
32	Punica granatum L.	Lythraceae	Pomegranate	Fruit peel	47	−
				Seeds	48	−
33	Acacia farnesiana (L.) Willd.	Fabaceae	Thorn Mimosa	Seeds	49	−
34	Coriandrum sativum L.	Apiaceae	Coriander	Seeds	50	−
35	Citrus maxima (Burm.) Merr.	Rutaceae	Chinese grapefruit	Peel	51	−