Single-Dose Toxicity Study on ML171, a Selective NOX1 Inhibitor, in Mice

Figure 2

Histology of the liver. G1/0 (a, d) is vehicle control groups. Mild fibrosis of the membrane and inflammatory cell infiltration were observed in the G4/250 (b) and G5/500 (c) groups. Hepatocytes were hypertrophic in centrilobular areas and increased mitosis occurred in the G4/250 (e) and G5/500 (f) groups.

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