Association Analysis of LEP Signaling Pathway with Type 2 Diabetes Mellitus in Chinese Han Population from South China

Table 9

Results of haplotype unconditional logistic regression analysis of 8 genes in LD block in the LEP signaling pathway.

Gene	SNP		SNP		Freq	OR (95% CI)
LEP	rs2167270	G	rs4731426	C	0.695	1.00	—
		A		G	0.238	1.14 (0.99-1.32)	0.076
		G		G	0.067	0.99 (0.77-1.27)	0.921
JAK1	rs10889502	C	rs17127107	C	0.352	1.00	—
		G		C	0.333	1.09 (0.94-1.27)	0.261
		C		G	0.304	1.07 (0.91-1.25)	0.411
		G		G	0.011	1.57 (0.74-3.37)	0.240
PPARGC1A	rs2970847	C	rs6821591	T	0.673	1.00	—
		T		C	0.238	1.00 (0.86-1.15)	0.950
		C		C	0.087	0.95 (0.76-1.19)	0.674
PRKAA1	rs249429	T	rs3805486	A	0.546	1.00	—
		T		G	0.234	1.01 (0.87-1.18)	0.881
		C		A	0.221	1.05 (0.90-1.23)	0.532
PRKAA2	rs1342382	T	rs6588640	G	0.496	1.00	—
		A		G	0.253	0.95 (0.82-1.11)	0.531
		T		A	0.250	0.93 (0.80-1.07)	0.300
PRKAB2	rs3766522	A	rs6937	C	0.541	1.00	—
		A		T	0.340	1.05 (0.92-1.21)	0.481
		T		T	0.118	1.14 (0.93-1.39)	0.212
PRKAG2	rs2970847	C	rs6821591	T	0.673	1.00	—
		T		C	0.238	1.00 (0.86-1.15)	0.951
		C		C	0.087	0.95 (0.76-1.19)	0.673
PRKAG3	rs6436094	A	rs645163	C	0.433	1.00	—
		G		T	0.422	1.02 (0.89-1.16)	0.801
		G		C	0.137	0.95 (0.79-1.15)	0.621