Hippocampal Subfield Volumes in Major Depressive Disorder Adolescents with a History of Suicide Attempt

Table 2

Hippocampal subfield volume difference between healthy controls, patient controls, and suicide attempters with MDD.

Subfields	HC ()	PC ()	SA ()				HC vs. PC	HC vs. SA	PC vs SA
Left whole
Left hippocampal tail				0.426	0.654	1.000	1.000	1.000	1.000
Left subiculum				0.197	0.822	1.000	1.000	1.000	1.000
Left CA1				0.395	0.675	1.000	1.000	1.000	1.000
Left hippocampal fissure				7.900	0.001	0.012	0.002	1.000	0.001
Left presubiculum				0.293	0.747	1.000	1.000	1.000	1.000
Left parasubiculum				1.585	0.210	1.000	1.000	0.258	0.787
Left molecular-layer-HP				0.422	0.657	1.000	1.000	1.000	1.000
Left GC-ML-DG				0.735	0.482	1.000	0.763	1.000	0.963
Left CA3				0.718	0.490	1.000	0.839	1.000	1.000
Left CA4				0.740	0.480	1.000	0.751	1.000	0.974
Left fimbria				3.319	0.004	0.032	0.436	1.000	0.181
Left HATA				0.344	0.709	1.000	1.000	1.000	1.000
Right whole
Right hippocampal tail				0.835	0.437	1.000	1.000	1.000	0.738
Right subiculum				0.012	0.988	1.000	1.000	1.000	0.705
Right CA1				0.129	0.879	1.000	1.000	1.000	1.000
Right hippocampal fissure				9.161	<0.001	<0.001	0.001	1.000	0.001
Right presubiculum				0.452	0.638	1.000	1.000	1.000	1.000
Right parasubiculum				1.791	0.172	1.000	0.287	0.375	1.000
Right molecular-layer-HP				0.082	0.922	0.998	1.000	1.000	1.000
Right GC-ML-DG				0.983	0.378	1.000	0.496	1.000	1.000
Right CA3				1.762	0.177	1.000	0.269	0.431	1.000
Right CA4				1.238	0.295	1.000	0.356	1.000	1.000
Right fimbria				3.108	0.007	0.042	0.459	1.000	0.342
Right HATA				0.592	0.555	1.000	0.974	1.000	1.000

^aBonferroni corrected for multiple comparisons between the groups. , . Abbreviations: SA: suicide attempters; PC: patient controls; HC: healthy controls; CA: cornu ammonis; GC-DG: granule cell layer of dentate gyrus; HATA: hippocampus-amygdala transition area; FDR: false discovery rate.