Uncovering the Mechanisms and Molecular Targets of Weibing Formula 1 against Gastritis: Coupling Network Pharmacology with GEO Database

Table 3

The top 20 significantly enriched pathway between gastritis and normal control.

Name	Size	ES	NES	NOM val	FDR val	FWER val
Pathways in cancer	322	-0.444	-1.662		0.051	0.402
MAPK signaling pathway	264	-0.403	-1.47	0.004	0.104	0.841
Cytokine-cytokine receptor interaction	252	-0.706	-1.703		0.043	0.313
Regulation of actin cytoskeleton	211	-0.362	-1.396	0.03	0.142	0.913
Focal adhesion	197	-0.463	-1.491	0.045	0.09	0.804
Chemokine signaling pathway	183	-0.747	-1.793		0.039	0.146
Endocytosis	176	-0.407	-1.86	0.004	0.028	0.079
Jak Stat signaling pathway	147	-0.572	-1.731		0.044	0.247
Alzheimer’s disease	143	-0.384	-1.463	0.032	0.107	0.848
Insulin signaling pathway	137	-0.356	-1.45	0.046	0.115	0.864
Cell adhesion molecules (CAMs)	130	-0.701	-1.652		0.053	0.425
Natural killer cell-mediated cytotoxicity	124	-0.634	-1.707		0.044	0.304
Neurotrophin signaling pathway	124	-0.407	-1.624	0.011	0.052	0.502
Leukocyte transendothelial migration	115	-0.645	-1.686		0.044	0.348
Vascular smooth muscle contraction	112	-0.468	-1.431	0.016	0.127	0.884
T cell receptor signaling pathway	106	-0.641	-1.758		0.043	0.2
Melanogenesis	101	-0.414	-1.409	0.032	0.135	0.899
GnRH signaling pathway	100	-0.439	-1.528	0.01	0.071	0.734
Parkinson’s disease	98	-0.41	-1.584	0.025	0.065	0.615
Toll-like receptor signaling pathway	96	-0.681	-1.77		0.042	0.175