Investigation of Plantago ovata Husk as Pharmaceutical Excipient for Solid Dosage Form (Orodispersible Tablets)

Table 1

Composition of various formulations of orodispersible tablets of domperidone containing PO husk as disintegrant, prepared by direct compression technique.

Ingredients	F-1 (control)	F-2	F-3	F-4	F-5	F-6	F-7
Domperidone	6.67	6.67	6.67	6.67	6.67	6.67	6.67
Flavor (orange)	0.50	0.50	0.50	0.50	0.50	0.50	0.50
Aspartame (sweetener)	3.00	3.00	3.00	3.00	3.00	3.00	3.00
Primojel	3.00	—	—	—	2.50	—	—
Plantago ovata husk	—	3.00	5.00	7.50	2.50	10.00	15.00
Microcrystalline cellulose (Ph102)	50.00	50.00	50.00	50.00	50.00	50.00	50.00
Tablettose-80	35.33	35.33	33.33	30.83	33.33	28.33	23.33
Magnesium stearate	1.50	1.50	1.50	1.50	1.50	1.50	1.50

Note: quantities are given in % ().