Comparing the Effect of Neostigmine and Metoclopramide on Gastric Residual Volume of Mechanically Ventilated Patients in Intensive Care Unit: A Double-Blind Randomized Clinical Trial

Table 3

Gastric residual volume (GRV) improvement at 3-, 6-, 9-, and 12-hour follow-up in two groups of study.

GRV	Time trend					value	value
	Baseline	3 h	6 h	9 h	12 h
Neostigmine
<120 cc	0 (0)	38 (38.0)	55 (55.0)	93 (93.0)	100 (100)	<0.001	0.012
>120 cc	100 (100)	62 (62.0)	45 (45.0)	7 (7.0)	0 (0)
Metoclopramide
<120 cc	0 (0)	18 (18.0)	29 (29.0)	72 (72.0)	100 (100)
>120 cc	100 (100)	82 (82.0)	71 (71.0)	28 (28.0)	0 (0)
value	1	0.003	<0.001	<0.001	1

Independent -test between two groups; repeated measurement of time trend in the GEE model; comparison of change from respective baseline between the neostigmine and metoclopramide groups using the GEE model to control for time effect and sex and gender stay period in the repeated measurement.