Identifying Infliximab- (IFX-) Responsive Blood Signatures for the Treatment of Rheumatoid Arthritis

Figure 1

Entire procedures to investigate the blood gene expression profiles of rheumatoid arthritis patients. Profiles are retrieved from Gene Expression Omnibus, which are analyzed by the Monte Carlo feature selection method. A feature list is obtained, which is fed into the incremental feature selection method to construct efficient classifiers and extract essential genes. On the other hand, informative features, which are some top features in the list, are used to construct classification rules via Johnson Reducer and RIPPER algorithms.