Gentiopicroside Produces Endothelium-Independent Vasodilation by Deactivating the PI3K/Akt/Rho-Kinase Pathway in Isolated Rat Thoracic Aorta

<div>Effects of dilated mediators, including L-NAME, indomethacin (INDO), and methylene blue (MB) on GPS- (20, 80, and 160 <i>μ</i>M) induced vasorelaxation in endothelium-intact aortic rings precontracted with PE. 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BioMed Research International

fig2

Figure 2

Figure 2: Gentiopicroside Produces Endothelium-Independent Vasodilation by Deactivating the PI3K/Akt/Rho-Kinase Pathway in Isolated Rat Thoracic Aorta 

Figure 2 | Gentiopicroside Produces Endothelium-Independent Vasodilation by Deactivating the PI3K/Akt/Rho-Kinase Pathway in Isolated Rat Thoracic Aorta 