Interaction of Adiponectin Genotypes and Insulin Resistance on the Occurrence of Taiwanese Metabolic Syndrome
Table 3
Interactions of apM1 +45, TNF-α -308 genotypes with fasting plasma glucose, and HOMA-IR on the development of Taiwanese metabolic syndrome.
Variables
apM1 +45 genotypes
TNF-α -308 genotypes
TT
GG/GT
AA/AG
GG
With/without MetS# (OR (95% CI))†
With/without MetS# (OR (95% CI))†
With/without MetS# (OR (95% CI))†
With/without MetS# (OR (95% CI))†
Fasting plasma glucose
≥ 100 mg/dL
44/28
7.59 (3.69-15.63)
32/24
5.86 (2.79-12.32)
19/13
6.47 (2.75-15.24)
57/39
5.99 (3.31-10.82)
< 100 mg/dL
23/72
1.20 (0.62-2.35)
22/84
1.00 (ref.)
7/27
0.95 (0.38-2.37)
38/129
1.00 (ref.)
Test for interaction
(1 df);
(1 df);
HOMA-IR
≥ 2.0
30/18
5.91 (2.78-12.54)
30/24
4.35 (2.14-8.85)
10/6
4.35 (1.47-12.87)
50/36
4.25 (2.27-7.41)
< 2.0
37/82
1.58 (0.86-2.88)
24/84
1.00 (ref.)
16/34
1.47 (0.73-2.95)
45/132
1.00 (ref.)
Test for interaction
(1 df);
(1 df);
#Indicated the numbers of subjects with and without MetS, respectively. †Adjusted the effects of age and gender. OR: odds ratio; CI: confidence interval; HOMA-IR: homeostatic model assessment for insulin resistance; ref.: reference. The value is < 0.01.
