Fisetin Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Macrophage
Effects of fisetin on the expression of inflammatory mediators in macrophages stimulated with LPS. (a) mRNA expression of MCP-1, IL-1β, and iNOS in LPS- (10 ng/mL) stimulated macrophages in the presence or absence of fisetin (10-100 μM) by qPCR ( in each group). Each bar presents the of six experiments. vs. control group; # vs. LPS-stimulated group. (b) NO concentration in each cell culture supernatants by colorimetric assay ( in each group). Each bar presents the of three experiments. vs. control; # vs. LPS.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.