Expression Pattern and Prognostic Value of EPHA/EFNA in Breast Cancer by Bioinformatics Analysis: Revealing Its Importance in Chemotherapy

Table 1

Association between EPHA/EFNA mRNA expression and clinicopathological features of patients with breast cancer.

(a)

Parameters	EPHA1	EPHA2	EPHA3	EPHA4	EPHA5	EPHA6
Age (years)	0.2250			0.3583	0.8373	0.1242
>51
≤51		0.0002	<0.0001
Nodal status	0.9075		0.6126	0.5222	0.9379	0.2129
Negative		0.0142
Positive
ER (IHC)					0.2271
Negative	<0.0001	<0.0001		<0.0001
Positive			<0.0001			0.0015
PR (IHC)					0.2851
Negative	<0.0001	<0.0001		<0.0001
Positive			<0.0001			0.0066
HER2 (IHC)			0.1385	0.7082	0.4015
Negative						0.0031
Positive	<0.0001	<0.0001
Triple-negative status					0.0924	0.4042
Not			<0.0001
TNBC	<0.0001	<0.0001		<0.0001
P53 sequence				0.2714	0.5513
Wild type			<0.0001			0.0035
Mutated	<0.0001	<0.0001

(b)

Parameters	EPHA7	EPHA10	EFNA1	EFNA3	EFNA4	EFNA5
Age (years)	0.0577	0.0878
>51			<0.0001	0.0092
≤51					0.0003	<0.0001
Nodal status	0.9157	0.7342	0.4045		0.6819	0.7867
Negative
Positive				0.0482
ER (IHC)
Negative	<0.0001			<0.0001	<0.0001	<0.0001
Positive		<0.0001	<0.0001
PR (IHC)		0.5102
Negative	0.0046			<0.0001	<0.0001	<0.0001
Positive			<0.0001
HER2 (IHC)	0.9010	0.9299				0.5285
Negative			<0.0001
Positive				<0.0001	<0.0001
Triple-negative status			0.3715
Not		0.0333
TNBC	0.0002			<0.0001	<0.0001	<0.0001
P53 sequence	0.4840	0.1113
Wild type			0.0206
Mutated				<0.0001	<0.0001	<0.0001