Review Article

Surgical Site Infections and Perioperative Optimization of Host Immunity by Selection of Anesthetics

Table 1

Strong recommendations by WHO.

Preoperative
(i) Decolonization with mupirocin ointment with or without chlorhexidine gluconate body wash in nasal carriers of Staphylococcus aureus undergoing cardiothoracic and orthopedic surgery.
(ii) Mechanical bowel preparation without the use of oral antibiotics
(iii) Hair removal
(iv) Prophylactic antibiotic should be administered within 120 minutes before incision, while considering the half-life of the antibiotic.
(v) Surgical hand preparation should be performed either by scrubbing within a suitable antimicrobial soap and water or using a suitable alcohol-based hand rub before donning sterile gloves.
(vi) Alcohol-based antiseptic solutions based on chlorohexidine (CHG) for surgical site skin preparation should be used in patients undergoing surgical procedures.
Intraoperative/postoperative
(i) Perioperative oxygenation
(ii) Surgical antibiotic prophylaxis administration should not be prolonged after completion of the operation.