Research Article

Chemometric Analysis of UV-Visible Spectral Fingerprints for the Discrimination and Quantification of Clinical Anthracycline Drug Preparation Used in Oncology

Table 3

Performance results of the quantification models developed for all concentration ranges of the three drugs.

DoxorubicinDaunorubicinEpirubicin

Concentration range mg/mL0.001-0.0640.006-0.0770.006-0.083
Spectral pretreatmentRawRawRaw
Number of variables latent111
-square of calibration0.990.990.99
-square of crossvalidation0.990.990.99
RMSECV0.000370.001790.00125
RMSEC0.000330.001620.00089