Cediranib Induces Apoptosis, G1 Phase Cell Cycle Arrest, and Autophagy in Non-Small-Cell Lung Cancer Cell A549 In Vitro

Figure 6

Effect of CED on proteins involved in VEGFR/Akt/mTOR and VEGFR/MAPK pathway in A549 cells after 48 h treatment. (a, c) Representative western blot images. (b, d) Quantitative analysis of the expression of VEGFR2, VEGFR3, Akt, p-Akt, p-38, p-p38, Erk, p-Erk, mTOR, and p-mTOR, as represented by column graphs. GAPDH was used as a control. All data are representative of three independent experiments. The data are expressed as the . , , and (vs. control group).

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