[Retracted] Identification of Hearing Loss-Associated Variants of PTPRQ, MYO15A, and SERPINB6 in Pakistani Families

Figure 1

Family pedigrees, hearing loss (HL) phenotype and causative alleles. (a) Segregation of HL causing alleles in three Pakistani families. Double lines indicate consanguineous families, empty symbols represent unaffected individuals, and filled symbols affected individuals. The genotypes of the identified variants are also shown for each of the participating family members. All families had autosomal recessive mode of inheritance for HL. (b) Audiometric air conduction thresholds from the proband of each Pakistani family revealed varying degree of HL. (c) ClustalW multiple amino acid sequence alignment shows evolutionary conservation of arginine at position 360 of SERPINB6.

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