Score for Predicting Active Cancer in Patients with Ischemic Stroke: A Retrospective Study
Table 1
Comparison of baseline characteristics between patients with ischemic stroke and active cancer and those without cancer.
Variables
Cancer group
Control group
value
Demographics
Age (years)
3.00
<0.01
Sex (% male)
34 (64.2)
522 (70.0)
0.79
0.37
Vascular risk factors
Hypertension
30 (56.6)
508 (68.1)
2.97
0.09
Diabetes mellitus
14 (26.4)
286 (38.3)
3.00
0.08
Hyperlipidemia
12 (22.6)
368 (49.3)
14.13
<0.01
Atrial fibrillation
4 (7.6)
46 (6.2)
0.57
Coronary heart disease
8 (15.1)
106 (14.2)
0.03
0.86
Previous stroke/TIA
7 (13.2)
129 (17.3)
0.59
0.45
Current smoking
25 (47.2)
351 (47.1)
0.00
0.99
Obesity
6 (11.3)
121 (16.2)
0.89
0.35
TOAST classification
Large-artery atherosclerosis
5 (9.4)
455 (61.0)
53.85
<0.01
Cardioembolism
2 (3.8)
33 (4.4)
1.00
Small vessel occlusion
9 (17.0)
216 (29.0)
3.51
0.06
Other determined etiology
2 (3.8)
11 (1.5)
0.21
Undetermined etiology
35 (66.0)
31 (4.2)
250.6
<0.01
Ischemic stroke characteristics
Initial NIHSS score
2.89
<0.01
AMCI
30 (56.6)
148 (19.8)
38.63
<0.01
VTE or PE
7 (13.2)
28 (3.8)
10.56
<0.01
Laboratory markers
Hemoglobin (g/L)
-6.63
<0.01
Platelets (/109)
-0.64
0.53
Fibrinogen (g/L)
3.49
<0.01
D-dimer (mg/mL)
2.23 (0.98–10.76)
0.35 (0.27–0.48)
-9.55
<0.01
CRP (mg/L)
18.40 (5.45–46.00)
3.90 (2.80–6.33)
-7.35
<0.01
Data are presented as the , median (interquartile range), or (%). Abbreviations: AMCI: acute multiple cerebral infarctions; VTE: venous thromboembolism; PE: pulmonary embolism; CRP: C-reactive protein; NIHSS: National Institute of Health Stroke Scale; TOAST: Trial of Org 10172 in Acute Stroke Treatment; TIA: transient ischemic attack.
