Knockdown of Gastrin Promotes Apoptosis of Gastric Cancer Cells by Decreasing ROS Generation

<div>Knockdown of gastrin affects the mitochondrial membrane potential. (a) JC-1 staining was detected cell mitochondrial membrane potential and analyzed by laser-scanning confocal microscopy. The images showed representative fluorescence micrographs of JC-1-stained gastrin KD cells and control cells. (b) Mitochondrial membrane potential evaluated by JC-1 staining and analyzed by flow cytometry. Cell populations with higher and lower JC-1 aggregated staining are marked with high percentage of p3 and low percentage of p3, respectively. A decrease in the p3 indicates a rise in mitochondrial membrane potential. 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BioMed Research International

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Figure 3

Figure 3: Knockdown of Gastrin Promotes Apoptosis of Gastric Cancer Cells by Decreasing ROS Generation 